The following directory lists the graduate courses which the University expects to offer, although the University in no way guarantees that all such courses will be offered in any given academic year, and reserves the right to alter the list if conditions warrant. Click on the links below for a list of courses in that subject area. You may then click “View Classes” to see scheduled classes for individual courses.
Grading Basis: Graded
Mechanistic toxicology describes the processes of how chemicals exert their toxic effects in biological systems. Therefore, understanding of the underlying mechanisms of toxicity, together with exposure estimates, provides key information that links the toxic hazard of a chemical with the actual human health risk. This first course explores some fundamental cellular and molecular mechanisms of toxicity and integrates them into a larger picture; reactive intermediates, oxidative and nitrative stress, and mitochondria-mediated toxicity will be covered. The basic concepts will be illustrated with specific examples (drugs and environmental chemicals).
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